galenIQ™ 721 for Direct Compression

Agglomerated isomalt (Ph.Eur./BP/USP-NF)

SEM photograph of galenIQ™ 721, magnification 400 x
galenIQ™ 721 is a high soluble agglomerated spherical isomalt for direct compression applications.
 General benefits      
  • Non-animal origin
  • Very low hygroscopic
  • Grades with different solubilities available
  • Excellent chemical stability, e.g. no reaction with amino groups
  • Highly resistant against degradation by enzymes and acids
  • Generally regarded as a non-toxic, non-allergic and non-irritant material
  • Non-cariogenic and very low glycemic response
  • GMO-free
  • Pleasant sugar-like, natural sweet taste profile
Properties        

  • Solubility 42 g/100 g solution at 20 °C in water
  • High agglomerate stability and excellent flow
  • Morphology ensures homogeneity of the mix and content uniformity
  • Very low compression forces required
  • Filler and binder function – high dilution potential
  • Low and high dosage formulations
  • Slow to very fast disintegrating tablets
  • Addition of other binders is in general not required to improve tablet hardness
  • Only standard amounts of lubricants required
  • Low Mg-stearate susceptibility
Preferred Application: Tableting and Capsule Filling        

  • Low and high dosage direct compression
  • Very fast disintegrating tablets
  • Oro dispersible tablets due to excellent taste
  • Use min. 25 % m/m to enhance the tablet hardness in your formulation
Additional Information        

Isomalt is listed in the FDA/CDER list of inactive ingredient database http://www.accessdata.fda.gov/scripts/cder/iig/
 
Physical properties of galenIQ™ 721: Download (JPEG, 139.38 KB)